Journal de la science cellulaire et des mutations

Abstrait

Study of management on comorbid conditions in type-2 diabetes mellitus

Arun Kumar S, Subba Rao Ch, Priyanka D

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia; is associated with abnormalities in carbohydrates, fat, and protein metabolism; and results in chronic complications including microvascular, macrovascular, and neuropathic disorders. The long term complications include retinopathy with potential blindness, nephropathy with kidney failure and neuropathy with risk of foot ulcers, amputation, and Charcot joint and sexual dysfunction. Macrovascular event is responsible for 75% of deaths in patients having type-2 DM. Multiple risk factors are responsible for developing type-2 DM, which include family history, obesity, habitual physical activity, race or ethnicity, previously identified impaired glucose tolerance or impaired fasting glucose, hypertension, high density lipoprotein cholesterol and triglyceride. This study is done to manage the comorbid conditions of diabetes mellitus. This study is a prospective observational study which was conducted over a period of 6 months among type-2 diabetic patients attending at an out-patient department of Care Diabetes Center, Hanamakonda, Warangal, Andhra Pradesh. This study took place between March and September 2013. Collected all relevant information from the patient’s case sheets, laboratory reports, patients care taker, treatment charts and counseling. All the collected information documented properly by data collection form. Out of 554 patients was enrolled into the study. Among them 252 (45.48%) of these patients were men and 302 (54.52%) were females respectively. 58.48% (324) were associated with macrovascular complications and 33.39% (185) were associated with microvascular complications. This study was conducted to increase prevalence of disease, through creating awareness about drug treatment and diabetic complications. Among the various complications, macrovascular complications caused major threat and among macrovascular complications, Hyperlipidemia and hypertension are major causes. Prophylaxis was done for patient’s inorder to prevent the further complication of diabetes mellitus.