Abstrait

Genotoxicity of Noscapine Nanosuspension on DU145 Human Prostate Cancer (Spheroid Cell Model)

Setare Kakavand Malayera, Hedieh Ghourchian , Maryam Azarian

 In Iranian folk medicine, the cytotoxic effects of some members of the papaveraceae family have been reported. Recent reports have shown that the fraction of opium alkaloids may be responsible for its cytotoxic effect, but this mechanism is not fully understood. This study was designed to investigate the selective cytotoxic and genotoxic effects on DU145 cancer cell lines of noscapine one non-addictable opium alkaloids.