Abstrait

Eosinophilic pancreatitis need an attention.

Murli Manohar*

Inflammatory diseases include a vast array of disorders and conditions that are characterized by inflammation, such as allergy, asthma, eosinophilic gastrointestinal disorders including pancreatitis [1-6]. The data indicates, 13 to 45/100,000 people in United States are having acute pancreatitis (AP) annually, whereas, chronic pancreatitis (CP) varies from 4.4 to 11.9/100,000 [1-3]. Pancreatitis is the inflammation of pancreas and arises due to several reasons such as alcohol abuse, mutation in trypsinogen gene, gallstones, and several drugs and food induced. Pancreatitis is of two types; the initial shock of pancreatitis is called acute pancreatitis and when these episodes frequency occurs several time it leads chronic pancreatitis. Pancreatic inflammation is characterized by destruction of acinar cells, which lead activation of several inflammatory cells like mast cells, neutrophils, macrophages and granulocytes such as basophils and eosinophils that secrete several pro-inflammatory cytokines [2,3].