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Coronavirus Disease-19(COVID-19) infection during pregnancy: Report of two cases and review of the literature

Ling Ming*, Huang Li, Huang Furong, Xu Jun, Yang Wenjuan, Dengludan, Zhang Aimin

In this article, we report the diagnosis and treatment of two patients with SARS-CoV-2 (severe acute respiratory syndrom coronavirus-2) infection in Hunan Province, China, and their perinatal outcomes. Two patients were admitted to the hospital due to full-term pregnancy with no fever or gastrointestinal symptoms noted during admission. However, they developed fevers and a dry cough on the day of and the third day after cesarean section; and both patients were found to be positive for SARS-CoV-2 by RT-qPCR for viral nucleic acid after symptoms appeared. After a detailed examination and history, one patient's husband proved to have had contact with whom travelled to Hubei and then this patient was found to be negative for SARS-CoV-2 and discharged after isolation and symptomatic supportive treatment. We did not detect SARS-CoV-2 in neonatal throat swabs. After isolation, the newborn recovered and was discharged.