Abstrait

Antimicrobial peptides in mycobacterial therapy

Farzaneh Mohammadzadeh Rostami

Infectious diseases are one of the leading causes of death worldwide, especially in underdeveloped and developing countries. Currently, the prevalence of drug-resistant Mycobacterium tuberculosis isolates, especially multidrug-resistant isolates and isolates with widespread drug resistance, is increasing, which is a serious threat to health systems. Second-line TB drugs cost more and have more side effects for patients. Numerous studies have shown that antimicrobial peptides and bacteriocins play an important role as antibacterial properties. Global efforts to reduce the prevalence of tuberculosis, coupled with the rapid growth of resistant strains, have increased interest in peptide compounds as new sources for treatment.