Gynécologie et endocrinologie de la reproduction

Abstrait

A lion?s heart, a newly diagnosed case of radiation-induced heart disease (myocardial ischemia) in a multigravid previously treated for hodgkin?s lymphoma: An interesting case

Kia Angela B. Gargantiel

Radiation therapy plays a pivotal role in the treatment of various thoracic malignancies. Radiation Induced Heart Disease (RIHD) is one long term toxicity which can offset the improvement in cancer specific mortality. Survivors of Hodgkin Disease are at a greater risk of RIHD because they have a relatively longer cancer specific survival. This is a case of M.M., a 26 year old G2P2 who underwent chemotherapy and radiotherapy at 19 years of age for Hodgkins Lymphoma. Seven years after, while on her second pregnancy, she was diagnosed to have Radiation Induced Acute Coronary Syndrome at 8 weeks AOG by EUTZ. She was exposed to high doses of antiplatelet and anticoagulant medications, and was subjected to a Coronary Angiogram revealing a 2-vessel disease thus a Percutaneous Coronary Intervention of the Left Main and Proximal Left Anterior Descending Artery was done. She was exposed to the teratogenic effects of x-rays and other medications during the first trimester of her pregnancy. She was able to deliver at 38 1/7 weeks AOG by EUTZ via Low Transverse Cesarean Section II to a live male neonate, BW 7 lbs 6 oz, AS 911955. She was able to bring her pregnancy to term without any compromise despite the exposure to treatment that could have otherwise compromised her pregnancy.

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